Merck
AI-Driven Chemical Synthesis Solutions
Accelerating the Entire Workflow from Molecular Design to Synthesis
Merck offers industry-leading AI-driven chemical synthesis solutions that integrate retrosynthesis planning with AI molecular design technology. SYNTHIA™ retrosynthesis software features 110,000+ hand-coded reaction rules and 21 years of development history (formerly known as Chematica), while AIDDISON™ is the industry's first AI platform that integrates virtual molecular design with real-world manufacturability.
The two products are deeply integrated via API, enabling a seamless workflow from AI molecular design to synthesis route planning, helping medicinal chemists complete in minutes what traditional methods require weeks to accomplish. AI technology is projected to save over $70 billion in drug discovery processes by 2028.
Merck Solutions
Innovative platforms combining AI technology with chemical expertise
SYNTHIA™
Retrosynthesis planning SaaS software with 110,000+ hand-coded reaction rules and 21 years of development history. Each analysis provides 50+ synthesis route suggestions, with support for green chemistry assessment and multi-target analysis.
Learn MoreAIDDISON™
AI drug discovery platform searching 60 billion+ compound space, trained on 20+ years of experimental data. Integrated with SYNTHIA retrosynthesis to ensure designed molecules are practically synthesizable. ISO 27001 certified.
Learn MoreAdvantages of AI Chemistry
Hand-Coded Reaction Rules
SYNTHIA features 110,000+ expert hand-coded reaction rules, ensuring the scientific reliability of synthesis routes
Compound Search Space
AIDDISON can screen molecules with successful drug properties from over 60 billion possible compounds
SaaS Cloud Architecture
Both products are cloud-based SaaS platforms requiring no local installation and supporting global collaboration
Seamless Design-to-Synthesis Integration
AIDDISON and SYNTHIA are deeply integrated via API, enabling real-time evaluation of designed molecule synthesizability
Application Areas
| Field | SYNTHIA Applications | AIDDISON Applications |
|---|---|---|
| Drug R&D | Drug synthesis route planning, green chemistry synthesis, process development | Lead compound design, target-directed molecular generation, ADMET optimization |
| Fine Chemicals | Specialty chemical synthesis, intermediate manufacturing, scale-up synthesis strategies | Functional molecular design, property optimization |
| Agrochemicals | Pesticide active ingredient synthesis routes, herbicide synthesis | Novel agrochemical molecular design |
| Academic Research | Synthesis teaching, chemistry research, methodology development | Molecular library design, structure-activity relationship studies |
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